Use of screening tests to assess cancer risk and to estimate the risk of adult T-cell leukemia/lymphoma.
نویسندگان
چکیده
We developed methods to assess the cancer risks by screening tests. These methods estimate the size of the high risk group adjusted for the characteristics of screening tests and estimate the incidence rates of cancer among the high risk group adjusted for the characteristics of the tests. A method was also developed for selecting the cut-off point of a screening test. Finally, the methods were applied to estimate the risk of the adult T-cell leukemia/lymphoma.
منابع مشابه
Hodgkin’s Lymphoma Occurring Secondary to Autologous Stem Cell Transplantation in Plasma Cell Leukemia; A Case Report
Survival of patients with multiple myeloma has improved substantially because of availability of new therapies including autotransplants, immunomodulating drugs and proteasome-inhibitors. Second primary cancers have emerged as an important determinant of morbidity and mortality among cancer survivors. Even though there is an increased risk of new cancers of the lymphoreticular and haematopoetic...
متن کاملHuman T Lymphotropic Virus Type I (HTLV-I) Oncogenesis: Molecular Aspects of Virus and Host Interactions in Pathogenesis of Adult T cell Leukemia/Lymphoma (ATL)
The study of tumor viruses paves the way for understanding the mechanisms of virus pathogenesis, including those involved in establishing infection and dissemination in the host tumor affecting immune-compromised patients. The processes ranging from viral infection to progressing malignancy are slow and usually insufficient for establishment of transformed cells that develop cancer in only ...
متن کاملSynergy between parthenolide and arsenic trioxide in adult T-cell leukemia/lymphoma cells in vitro
Objective(s): Adult T-cell leukemia/lymphoma (ATLL) is an aggressive lymphoid malignancy with low survival rate and distinct geographical distribution. In search for novel chemotherapeutics against ATLL, we investigated the combinatorial effects of parthenolide, a sesquiterpene lactone with valuable pharmaceutical activities, and arsenic trioxide (ATO) in vitro</em...
متن کاملDiffuse normolipemic plane Xanthoma in adult T-cell lymphoma/leukemia: A case report
Diffuse normolipemic plane xanthoma is a rare disorder often seen as a para-neoplastic manifestation accompanied with gammopathies and hematologic disorders. In this report, a 44-year-old man is presented who was referred to us due to developing erythematous papules on the hands and yellow patches on different parts of the body. Based on cell blood count, peripheral blood smear and positive ant...
متن کاملسرواپیدمیولوژی ویروس لنفوتروپیک سلول T انسانی(HTLV) در اهداکنندگان خون در شهر مشهد، سالهای 89-1388
Background and Aim: Human T-Cell Lymphotropic Virus (Type I) is the cause of two major diseases : Adult T cell Leukemia-Lymphoma and Tropical Spastic Paraparasia and Myelopathy associated with HTLV-I. Disease transmission is possible during unsafe sexual contact, blood transfusion and vertical transmission method. Blood safety and minimizing the risk of transfusion transmitted infections are th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Environmental Health Perspectives
دوره 87 شماره
صفحات -
تاریخ انتشار 1990